Comparison of topical isosorbide mononitrate, topical diltiazem, and their combination in the treatment of chronic anal fissure

Bulus H., Varol N., Tas A., COŞKUN A.

ASIAN JOURNAL OF SURGERY, vol.36, no.4, pp.165-169, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1016/j.asjsur.2013.01.010
  • Title of Journal : ASIAN JOURNAL OF SURGERY
  • Page Numbers: pp.165-169


Background/Objective: Chronic anal fissure is a painful condition that is associated with an increase in internal anal sphincter pressure. The main aim of this study is to evaluate the efficacy and adverse effects of topical isosorbide 5 mononitrate and topical diltiazem, when administered either as single agents or in combination, in the treatment of anal fissure.