Hypersexuality Associated With Paliperidone

ÇAYKÖYLÜ A., Karslioglu E. H., Ozer I., Koksal A. G.

EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY, vol.26, no.2, pp.109-112, 2018 (SCI-Expanded, SSCI, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.1037/pha0000178
  • Journal Name: EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.109-112
  • Ankara Yıldırım Beyazıt University Affiliated: Yes

Abstract

We report a case of unusual sexual symptoms in a 43-year-old female patient with schizophrenia (according to Diagnostic and Statistical Manual of Mental Disorders, fifth edition), who was being treated with a depot formulation of paliperidone palmitate, an atypical antipsychotic medication. The symptoms included increased sexual desire, sexual preoccupation, constant drive for intercourse, and sexual arousal with unrelated stimuli such as urination. Potential neurochemical mechanisms have been elucidated for this symptomatology. Paliperidone palmitate has broad neuropharmacological effects, which might have contributed to the development of this rare clinical condition.