Massive splenic infarction and portal vein thrombosis in children with chronic myeloid leukemia


Aksu T., Erdem A. Y. , Fettah A., Kaçar D., Avcí Z., Yarali N. , ...More

Journal of Pediatric Hematology/Oncology, vol.36, no.7, 2014 (Journal Indexed in SCI Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 7
  • Publication Date: 2014
  • Doi Number: 10.1097/mph.0000000000000204
  • Title of Journal : Journal of Pediatric Hematology/Oncology
  • Keywords: Childhood, Chronic myeloid leukemia, Splenectomy, Splenic infarct

Abstract

Copyright © 2013 by Lippincott Williams & Wilkins.Massive splenic infarction and portal vein thrombosis (PVT) due to chronic myeloid leukemia (CML) is extremely rare. We describe 2 children who were presented with massive splenic infarction and PVT in the course of CML. Massive splenic infarction and PVT treated with splenectomy in one and with medical treatment in another in whom PVT resolved by cytoreductive treatment, led to downsizing of spleen or splenectomy. Splenic infarct and PVT should be considered in CML patients with long-lasting severe abdominal pain despite appropriate medical attempts. Splenectomy should be spared for persistent symptoms and complications.