Parvovirus B19 infection reminiscent of myelodysplastic syndrome in three children with chronic hemolytic anemia
Pediatric Hematology and Oncology, cilt.17, sa.6, ss.475-482, 2000 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 17 Sayı: 6
- Basım Tarihi: 2000
- Doi Numarası: 10.1080/08880010050120836
- Dergi Adı: Pediatric Hematology and Oncology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.475-482
- Anahtar Kelimeler: MDS, Pancytopenia, Parvovirus B19
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır
Özet
The authors have seen transient pancytopenia with erythroid hypoplasia and striking trilineage myelodysplasia reminiscent of true myelodysplastic syndrome (MDS) in 3 children, 1 with thalassemia intermedia and the other 2 with previously undiagnosed hereditary spherocytosis. In these 3 children transient pancytopenia and myelodysplasia coincided with serological evidence of acute parvovirus-B19 (PV-B19) infection, strongly suggesting their relevance. It is of interest that these 3 cases were encountered within a period of 6 months. This might be an incidental event, but it might also be concluded that acute PV-B19 infection associated transient pancytopenia with morphological appearance of MDS may occur more frequently than reported in the literature. So, PV-B19-associated nonclonal MDS should be considered in the differential diagnosis of true clonal MDS.