Glutathione and malondialdehyde levels in patients with hydatid cyst
Saudi Medical Journal, cilt.29, sa.1, ss.87-89, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 1
- Basım Tarihi: 2008
- Dergi Adı: Saudi Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.87-89
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır
Özet
Objective: To investigate the levels of glutathione (GSH), and malondialdehide (MDA) in the sera of patients diagnosed with cyst hydatid. Methods: Forty-six hydatid cyst patients who were indirect hemaglutination (IHA) and indirect fluorescence antibody (IFA) test positive constituted our study group in 2007. Patients diagnosed with hydatid cyst in the Inonu University School of Medicine, Department of Parasitology were re-called for the study. Forty healthy subjects who were negative for hydatid cyst by IHA and IFA methods, and who did not have any parasites on stool inspection formed the control group. The MDA level was analysed in the sera by Uchiyama and Mihara method. The GSH activity was measured by the Ellman method. Results: The GSH level was 11.31 ± 3.80 μmol/L and the MDA level was 67.94 ± 106.70 μmol/L in the study group, while they were 24.95 ± 6.55 μmol/L and 26.52 ± 19.42 μmol/L in the control group. Conclusion: An increase in MDA levels and a decrease in GSH activity in patients with hydatid cyst was observed.