Genetic Polymorphisms in the Wrestling Branch
EDUCATION AS A TRANSFORMATIVE FORCE: INTERSECTIONS OF KNOWLEDGE, CULTURE, IDENTITY, AND PERFORMANCE, Prof. Dr. Earl JONES MUICO,Assoc. Prof. Dr. Ender Ali ULUÇ, Editör, Univ Delaware Press, Delaware, ss.81-102, 2025
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2025
- Yayınevi: Univ Delaware Press
- Basıldığı Şehir: Delaware
- Sayfa Sayıları: ss.81-102
- Editörler: Prof. Dr. Earl JONES MUICO,Assoc. Prof. Dr. Ender Ali ULUÇ, Editör
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
ABSTRACT
Objective: The aim of this review is to systematically elucidate the genetic polymorphisms influencing wrestling performance and to evaluate the implications of findings from endurance and power sports for wrestling. Methods: The literature search was performed using the PubMed, Scopus, Web of Science, SPORTDiscus, and Google Scholar databases, covering the period from 1999 to 2024. Studies involving human participants, athlete-based samples, and investigating the relationship between genetic variants and performance were included. Animal studies, clinical research, and publications without full-text access were excluded. A total of 30 peerreviewed research articles were included in the final analysis. Results: Wrestling-focused studies associate the ACTN3 R577X polymorphism with explosive power production and the EPAS1 rs1867785 A allele with elite success and oxygen utilization efficiency. The ACE I/D polymorphism demonstrates a mixed profile in restlers, while the MSTN K153R variant shows inconsistent relationships with muscle hypertrophy. IL-6 and VDR polymorphisms have been linked to recovery processes and bone metabolism, respectively. Findings from endurance and power ports corroborate these relationships, consistently reporting the R allele of ACTN3 with short-term power and EPAS1 variants with hypoxia adaptation and aerobic capacity. Conclusion: Given the hybrid nature of wrestling, which demands both power and endurance, the genetic markers investigated provide a significant biological substrate for explaining performance differences. However, contradictions in the existing data and limited sample sizes highlight a clear need for more extensive, multicentric studies adopting a polygenic approach, specifically tailored to wrestling. These findings establish a framework for future research and individualized training strategies.