Increased adenosine deaminase in hydatidiform mole
Clinical Chemistry and Laboratory Medicine, cilt.45, sa.1, ss.78-81, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 1
- Basım Tarihi: 2007
- Doi Numarası: 10.1515/cclm.2007.010
- Dergi Adı: Clinical Chemistry and Laboratory Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.78-81
- Anahtar Kelimeler: Adenosine deaminase, Hydatidiform mole
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır
Özet
Background: The aim of the current study was to investigate levels of adenosine deaminase in plasma of patients with hydatidiform mole. Methods: Plasma adenosine deaminase levels were determined in 17 women with normal pregnant course, in 17 women with hydatidiform mole, and in 17 non-pregnant healthy volunteers. Results: Mean adenosine deaminase activity in the hydatidiform mole group was 121.5±24.8 U/L, significantly higher than in the pregnant control (7.8±6.5 U/L; p<0.0001) and non-pregnant control groups (6.4±7.4 U/L; p<0.0001). A cutoff level of 40.5 U/L was found, with both sensitivity and specificity of 100%. Conclusions: Adenosine deaminase may play a role in the development of hydatidiform mole. © 2007 by Walter de Gruyter.