A case of steroid-resistance hashimoto's encephalopathy presenting with sensorimotor polyneuropathy


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Emeksiz S., Kutlu N. O., Alaçakır N., Çaksen H.

Turkish Journal of Pediatrics, vol.60, no.3, pp.310-314, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.24953/turkjped.2018.03.012
  • Journal Name: Turkish Journal of Pediatrics
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.310-314
  • Keywords: Auto-immune disease, Cyclophosphamide, Plasmapheresis, Sensorimotor polyneuropathy, Steroid-resistance Hashimoto’s encephalopathy
  • Ankara Yıldırım Beyazıt University Affiliated: No

Abstract

© 2018, Turkish Journal of Pediatrics. All rights reserved.Hashimoto’s encephalopathy (HE) is a rare, auto-immune disease characterized by symptoms of acute or subacute encephalopathy associated with increased anti-thyroid antibody levels. The course of most HE cases is relapsing and remitting, which is similar to that of vasculitis and stroke. Steroids are the first line treatment in HE. In steroid non-responders other immunomodulatory therapies or plasmapheresis could be applied. We report a case of steroid-resistance HE with sensorimotor polyneuropathy, as a rare presentation of this disorder. Our case showed that HE may present with sensorimotor polyneuropathy; therefore HE should be considered in the differential diagnoses of polyneuropathy.