Diagnosing atypia of undetermined significance in thyroid fine needle aspiration samples using nuclear scoring


Altinboga A. A. , ALTUNKAYA C., Ahsen H., Gumuskaya B., Topaloglu O., Ulusoy S., et al.

ANNALS OF DIAGNOSTIC PATHOLOGY, cilt.41, ss.112-115, 2019 (SCI İndekslerine Giren Dergi)

Özet

Background Atypia of undetermined significance (AUS) is an indeterminate category in the Bethesda system for reporting thyroid cytopathology. Cytological features described as atypia are not always observed in every case, and it is difficult to determine how the small population of cells with enlarged nuclei, a few grooves, and rare elongated nuclei should be classified. Therefore, there is inter-intra observer variability considering these cell types, even though the cytological criteria are well defined. Therefore, this study aimed to establish a nuclear scoring system to help in the differential diagnosis of AUS.