Fabrication of Nanopores in an Ultra-Thin Polyimide Membrane for Biomolecule Sensing


Guzel F. , Avci H.

IEEE Sensors Journal, cilt.18, sa.7, ss.2641-2646, 2018 (SCI Expanded İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Konu: 7
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1109/jsen.2018.2794781
  • Dergi Adı: IEEE Sensors Journal
  • Sayfa Sayıları: ss.2641-2646

Özet

Single molecule detection using nanopores has proven to be a powerful way of identifying biomolecules. There-fore, a variety of materials and methods have been developed by the nanopore community to generate credible outcomes. Here we report as the first time a novel polyimide nanopore platform for single DNA sensing. Novelty of the platform arises both from the ultra-thin structure of the polyimide membrane and also the technique used in the nanopore fabrication on a polymer membrane. Furthermore, the ultra-thin nature of the membrane eliminates the involvement of highly demanding fabrication steps often employed in the solid-state nanopore membrane production. Herein we present the fabrication of nanopores in such an ultrathin polymer membrane and its successful application in sensing DNA molecules at single molecule level, holding a promise as a potential single-molecule analytical device unlike its common use in research.