A Rare Clinical Course in Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: Lung Involvement
Pediatric, Allergy, Immunology, and Pulmonology, cilt.38, sa.3, ss.108-111, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 38 Sayı: 3
- Basım Tarihi: 2025
- Doi Numarası: 10.1177/2151321x251372016
- Dergi Adı: Pediatric, Allergy, Immunology, and Pulmonology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.108-111
- Anahtar Kelimeler: antibiotics, DRESS syndrome, pneumonitis
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Background: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a rare, potentially life-threatening hypersensitivity reaction characterized by skin rash, fever, eosinophilia, and multi-organ involvement. Although pulmonary complications are uncommon, they can significantly impact prognosis. Case Presentation: Here, we present a 6-year-old male with antibiotic-induced DRESS syndrome complicated by pleural effusion and pneumonitis. The patient was treated successfully with systemic corticosteroids and intravenous immunoglobulin following multidisciplinary evaluation. Conclusion: Pulmonary involvement in DRESS is frequently mistaken for pneumonia. This case highlights the importance of recognizing pulmonary involvement in DRESS syndrome and differentiating it from bacterial pneumonia, as misdiagnosis may lead to delayed corticosteroid treatment and unnecessary antibiotic use.