Heck’s Disease (Focal Epithelial Hyperplasia): A Case Contributing to Clinical and Histopathological Differential Diagnosis Heck Hastalığı (Fokal Epitelyal Hiperplazi): Klinik ve Histopatolojik Ayırıcı Tanıya Katkı Sunan Bir Olgu

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İYi̇Dal A. Y., Sahin M. D., Kandemir N. O., AKTAŞ A., KALKAN G.

Turkiye Klinikleri Dermatoloji, cilt.36, sa.1, ss.38-42, 2026 (Scopus)

Özet

Heck’s disease (focal epithelial hyperplasia) is a benign oral mucosal disease caused by human papillomavirus. It is frequently seen in children. Its higher frequency in certain geographic regions suggests genetic susceptibility to human papillomavirus. It can be confused with many diseases affecting the oral mucosa, especially other viral infections such as verruca vulgaris, squamous papilloma and condyloma acuminata. Therefore, not only dermatologists but also dentists who examine the oral mucosa, as well as otolaryngologists and pediatricians, should be well-acquainted with the clinical findings and, when necessary, request histopathological evaluation, as this is essential for accurate diagnosis, appropriate treatment, and effective follow-up. In this study, a 12-year-old boy patient with Heck’s disease detected in the lower lip and buccal mucosa is presented with his clinical and histopathological findings to shed light on further studies.