Chronic renal failure is a irreversible deterioration of the renal regulatory mechanisms of the fluid electrolyte balance and metabolic-endocrine functions as a result of reduced glomerular filtration rate. Hemodialysis, one of the renal replacement therapy options, is a treatment based on the exchange of fluid and solutes between the patient's blood and the appropriate dialysate through a semi-permeable membrane. Hemodialysis treatment has many complications. Patients experience many problems, such as reaction periods, psychological conflicts and tendency to deny, body image disorders, etc., when they start hemodialysis treatment. Both hemodialysis treatment and chronic renal failure cause changes in the biochemical parameters of patients. The excess of stressors, stressors are as versatile as physical psychology, the individual has negative effects on the quality of life. The stress is high and the continuity of the stressors is the basis for the alexitimia. A multidisciplinary treatment approach is important for the treatment to be monitored and the care to be planned, as patients have problems that require the combination of many disciplines.