The association between PTX3 and serum manganese levels of welders in comparison with controls: An application of anti-inflammatory biomarker
Journal of health sciences and medicine (Online), cilt.4, sa.4, ss.511-515, 2021 (TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 4 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.32322/jhsm.957953
- Dergi Adı: Journal of health sciences and medicine (Online)
- Derginin Tarandığı İndeksler: Directory of Open Access Journals, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.511-515
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Aim: The purpose of this study was to compare serum PTX3 levels of manganese-exposed welders with non-exposed controls to evaluate the nature of the manganese-induced inflammatory response. Material and Method: Overall, we collected 103 research samples (Mn-Exposed Welders Group:51 and Non-Exposed Controls: 52). PTX-3 levels were analyzed in the serum samples by the ELISA method, while Mn levels in whole blood specimens were quantified by the inductively coupled plasma (ICP-MS) method. Results: The mean values of manganese and Pentraxin-3 of the control group were found to be significantly lower than those of the exposure group (Mn levels: 5.04±2.32 μg/L vs. 11.54±3.09 μg/L; PTX-3: 36.96±24.20 ng/mL vs. 48.29±27.13 ng/mL; p<0.05). Conclusion: This hypothetical and observational investigation highlighted the relationship between Mn levels and PTX-3 for the first time.