Hemodilution is not the only reason of difference: Comparison of fasting and non-fasting lipoproteins in paired samples.


Iptec B. O., Balik A. R., Yuksel S., Yilmaz F. M., Yilmaz G.

Clinical biochemistry, cilt.61, ss.28-33, 2018 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.clinbiochem.2018.08.009
  • Dergi Adı: Clinical biochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.28-33
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

Introduction: Low-density lipoprotein cholesterol (LDL) is an important risk factor for cardiovascular disease (CVD) and generally measured after 8-12 h fasting. However, some recent studies have pointed that non-fasting lipoproteins, especially LDL concentrations, are better indicators for demonstrating CVD risk and atherosclerosis. They asserted that nutrition is a negligible factor on changes in lipoprotein concentrations and claimed this difference as a result of hemodilution effect, caused from fluid intake and can be eliminated by applying some adjustments. We aimed to compare the fasting and non-fasting LDL values of the same individuals and discuss whether non-fasting and fasting LDL results can be used in place of each other, directly or after applying hemodilution correction models.