Hemodilution is not the only reason of difference: Comparison of fasting and non-fasting lipoproteins in paired samples.

Iptec B. O. , Balik A. R. , Yuksel S., Yilmaz F. M. , Yilmaz G.

Clinical biochemistry, vol.61, pp.28-33, 2018 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61
  • Publication Date: 2018
  • Doi Number: 10.1016/j.clinbiochem.2018.08.009
  • Title of Journal : Clinical biochemistry
  • Page Numbers: pp.28-33


Introduction: Low-density lipoprotein cholesterol (LDL) is an important risk factor for cardiovascular disease (CVD) and generally measured after 8-12 h fasting. However, some recent studies have pointed that non-fasting lipoproteins, especially LDL concentrations, are better indicators for demonstrating CVD risk and atherosclerosis. They asserted that nutrition is a negligible factor on changes in lipoprotein concentrations and claimed this difference as a result of hemodilution effect, caused from fluid intake and can be eliminated by applying some adjustments. We aimed to compare the fasting and non-fasting LDL values of the same individuals and discuss whether non-fasting and fasting LDL results can be used in place of each other, directly or after applying hemodilution correction models.