EX VIVO CONFOCAL MICROSCOPY
MICROSCOPIC INVESTIGATIONS IN DERMATOLOGY, Murat Durdu, Editör, Turkiye Klinikleri, Ankara, ss.63-74, 2025
- Yayın Türü: Kitapta Bölüm / Mesleki Kitap
- Basım Tarihi: 2025
- Doi Numarası: 10.5336/978-625-395-777-3_p63
- Yayınevi: Turkiye Klinikleri
- Basıldığı Şehir: Ankara
- Sayfa Sayıları: ss.63-74
- Editörler: Murat Durdu, Editör
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
The incidence of skin cancer has been steadily rising over recent decades, highlighting the importance of advances in diagnostic technologies. In parallel, there have been rapid developments in cutaneous imaging methods that enable earlier and more accurate detection of these cancers. Commonly used in vivo modalities include dermatoscopy, reflectance confocal microscopy (RCM), and optical coherence tomography, each of which provides high-resolution visualization of skin lesions with substantial di-agnostic accuracy. Beyond these in vivo approaches, ex vivo RCM has emerged over the past decade as an innovative technique that facilitates bedside evaluation of excised tissue. This method allows rapid examination of specimens without the need for fixation or extensive tissue processing, thereby pro-viding near-immediate pathology results. Ex vivo RCM has already been successfully applied in fields such as breast pathology and has recently been translated into dermatology, where it shows promise for improving clinical workflow and patient care. The utilization of ex vivo RCM in dermatology is experiencing substantial growth, with its applications extending beyond skin and nail neoplasms to encompass inflammatory and infectious pathologies. In this review, we will outline the principles of ex vivo RCM, describe its features in skin tissue, and explore its potential applications in dermatologic practice.