From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic

Cetintav B., Yalcin A.

Animals, cilt.15, sa.2, 2025 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 2
  • Basım Tarihi: 2025
  • Doi Numarası: 10.3390/ani15020126
  • Dergi Adı: Animals
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Anahtar Kelimeler: equine colic, explainable artificial intelligence (XAI), machine learning in veterinary medicine, precision animal health management, SHAP, targeted veterinary medicine
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır

Özet

Colic is a leading cause of mortality in horses, demanding precise and timely interventions. This study integrates machine learning and explainable artificial intelligence (XAI) to predict survival outcomes in horses with colic, using clinical, procedural, and diagnostic data. Random forest and XGBoost emerged as top-performing models, achieving F1 scores of 85.9% and 86.1%, respectively. SHAP (Shapley additive explanations) was employed to provide interpretable insights, offering both global and local explanations for model predictions. The analysis revealed that key features, such as pulse rate, lesion type, and total protein levels, significantly influenced survival likelihood. Local interpretations highlighted the unique contribution of clinical factors to individual cases, enabling personalized insights that guide targeted treatment strategies. These tailored predictions empower veterinarians to prioritize interventions based on the specific conditions of each horse, moving beyond generalized care protocols. By combining predictive accuracy with interpretability, this study advances precision veterinary medicine, enhancing outcomes for equine colic cases and setting a benchmark for future applications of AI in animal health.