Hemophagocytic syndrome associated with bacterial infections

Yarali N., Yildirim I., Arik E., Zorlu P., Tanir G.

Cocuk Enfeksiyon Dergisi, vol.4, no.4, pp.162-164, 2010 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.5152/ced.2010.33
  • Journal Name: Cocuk Enfeksiyon Dergisi
  • Journal Indexes: Science Citation Index Expanded, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.162-164
  • Keywords: Beta hemolytic streptococcus, Hemophagocytic lymphohistiocytosis, Salmonella, Streptococcus pneumonia


Hemophagocytic lymphohistiocytosis (HLH) is characterized by systemic proliferation and activation of benign histiocytes showing hemophagocytosis. It can be classified as primary and secondary or acquired HLH. Secondary HLH is associated with several infections, autoimmune diseases and malignancies. Here we report three cases of hemophagocytic syndrome (HS) associated with diverse bacterial infections that resolved with appropriate antibacterial therapy.