The relation between lead exposure and inflammation / endothelial dysfunction
Medicine Science, cilt.9, sa.2, ss.468-472, 2020 (TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 9 Sayı: 2
- Basım Tarihi: 2020
- Doi Numarası: 10.5455/medscience.2020.08.9249
- Dergi Adı: Medicine Science
- Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.468-472
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Pb exposure is a well-known risk factor for inflammation including vessels. In our study, we aimed to investigate the relationship between Pb levels of exposed workersand the severity of inflammation/endothelial dysfunction. We analyzed the correlation between blood lead level and the markers of endothelial damage. There was a significantcorrelation between blood lead levels and vascular cell adhesion molecule-1 (VCAM-1). Elevated levels of blood lead also show correlation with soluble CD40ligand (sCD40L). The strongest correlation was with sE-selectin. Association between lead exposure and markers of cardiovascular injury may help to predict cardiovasculareffects of lead earlier and to protect workers who are exposed to lead.