Research Information System
European Journal of Cardio-thoracic Surgery, vol.9, no.6, pp.335-341, 1995 (Scopus)
Carpentier-Edwards (C/E) high profile supra-annular porcinebioprostheses were implanted in 163 patients between September 1982-February 1987 in the mitral position due to rheumatic disease. Thepatients' ages ranged between 15 and 58 years (mean: 36.5 +/- 11.5). Onehundred-two of the patients (62.5%) were female. The hospital mortality was9.8% (16/163). The total cumulative follow-up period was 1093 patient-years(p-y) with a mean of 7.3 +/- 3.5 p-y (range 6 months- 12 years). Linearisedoccurrence rates of the late complications were as follows: Thromboembolism0.82%/p-v, anticoagulant-related bleeding 1.0%/p-y, prosthetic valveendocarditis 0.09%/p-y. Actuarial survival rates for 5 and 12 years were87% +/- 6% and 76% +/- 9%, respectively, with 95% confidence limits.Freedom from structural deterioration was 92% +/- 5% for 5 years and 44%+/- 11% for 12 years. Freedom from all valve-related complications was 81%+/- 7 for 5 years and 26% +/- 9 for 12 years. In conclusion, thisprosthesis provides satisfactory clinical performance in young populationdespite the high risk of degeneration with good prognosis and bettertolerability of reoperation. © 1995, Springer-Verlag.