Homocysteine Concentrations in Heterozygote MTHFR (677C-T) and Factor V (1691 G-A) Mutation-carrying Individuals with the History of Thromboembolic Disease

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DOĞAN H. O. , Zungun C., YILMAZ F. M. , Kayalp D., ZARARSIZ G.

ERCIYES MEDICAL JOURNAL, vol.38, no.1, pp.20-24, 2016 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.5152/etd.2016.0060
  • Title of Journal : ERCIYES MEDICAL JOURNAL
  • Page Numbers: pp.20-24


Objective: Factor V (FV) (1691 G-A) and methylenetetrahydrofolate reductase (MTHFR) (677 C-T) mutations have been identified as potential risk factors for cardiovascular disease. In this study, we determined vitamin B-12, folate, and total homocysteine t(Hcy) concentrations in heterozygote MTHFR (677 C-T) and FV (1691 G-A) mutation-carrying individuals.