Detection of intramural fat accumulation by 3D-Dixon-Caipirinha-Vibe and the contribution of this technique to the determination of the chronicity of Chron's disease

Erol M. Y. , Algin O.

Magnetic Resonance Imaging, vol.85, pp.93-101, 2022 (Journal Indexed in SCI Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 85
  • Publication Date: 2022
  • Doi Number: 10.1016/j.mri.2021.10.018
  • Title of Journal : Magnetic Resonance Imaging
  • Page Numbers: pp.93-101
  • Keywords: CAIPIRINHA, DIXON, Inflammatory bowel diseases, Intramural fat accumulation, MR enterography (MRE)


© 2021 Elsevier Inc.Objectives: In this study; we aimed to evaluate the efficacy of the 3D-Dixon-Caipirinha-Vibe fat images in detecting intramural fat accumulation (IFA) and contributions of 3D-Dixon-Caipirinha-Vibe in the management of patients with Chron's disease. Methods: Eighty-five patients who had a 3-tesla MR enterography (MRE) with the 3D-Dixon-Caipirinha-Vibe technique were included. Wall thickness, ADC-value, intramural edema, presence/extension of IFA, and contrast-material enhancement of the affected segments were examined. Findings of MRE were compared statistically with clinical, laboratory, endoscopy, and pathological exams. Results: The presence of IFA was more common in patients with chronic active and chronic inflammation than only active inflammation and normal cases. Patients with IFA had a longer disease duration than patients without IFA. IFA-containing segment lengths of patients with chronic active inflammation and chronic inflammation were found to be longer than those with active inflammation. It was found that patients whose pathology results were reported as active inflammation contained less IFA than patients with chronic inflammation. Conclusions: The presence of IFA is strongly related to chronicity. 3D-Dixon-Caipirinha-Vibe is a fast, easy, and useful method for detecting IFA and evaluating Chron's disease.