Plasma Amino-Terminal Propeptide of C-Type Natriuretic Peptide Concentration in Normal-Weight and Obese Children.

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TOPÇU S., ÖZHAN B., Alkan A. , Akyol M., Orhon F. S. , BAŞKAN S., ...More

Journal of clinical research in pediatric endocrinology, vol.9, no.4, pp.308-314, 2017 (Journal Indexed in SCI Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.4274/jcrpe.4543
  • Title of Journal : Journal of clinical research in pediatric endocrinology
  • Page Numbers: pp.308-314


Objective: In studies on the relationship between amino-terminal propeptide of C-type natriuretic peptide (NT-proCNP) concentration and height velocity in children, CNP has been implicated as an emerging new growth marker during childhood. It has been reported that besides its well-studied role in growth, plasma CNP levels are reduced in overweight and/or obese adolescents, suggesting CNP as a potential biomarker in childhood obesity. The primary goal of this study was to test this hypothesis in a Turkish population.