An Investigation of the Effects of Curcumin on the Changes in the Central Nervous System of Rats Exposed to Aroclor 1254 in the Prenatal Period.

ALÇIĞIR M. E. , DOĞAN H. O. , Dikmen B. Y. , Dogan K. , Vural S. A. , YILMAZ F. M. , ...More

CNS & neurological disorders drug targets, vol.17, no.2, pp.132-143, 2018 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.2174/1871527317666180315170146
  • Title of Journal : CNS & neurological disorders drug targets
  • Page Numbers: pp.132-143


Background & Objective: Aroclor 1254 is a widespread toxic compound of Polychlorinated Biphenyls (PCBs), which can create significant nervous problems. No remedies have been found to date. The aim of this study was to reveal the damage that occurs in the central nervous system of rat pups exposed to Aroclor 1254 in the prenatal period and to show the inhibiting effect of curcumin, which is a strong anti-oxidant and neuroprotective substance.